ADENOSINE IN THE CENTRAL NERVOUS SYSTEM
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Abstract:
Besides being a metabolite of nucleotides like ATP, adenosine is a mediator of neuronal function in the central nervous system. Its actions are mediated by at least three extracellular receptors. In this review different aspects of adenosine such as biosynthesis, release, inactivation and its receptors are discussed. It also covers pre- and postsynaptic effects as well as postreceptor mechanisms of adenosine. Finally, therapeutic aspects of this neuromodulator have been discussed.
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Journal title
volume 9 issue 4
pages 361- 368
publication date 1996-02
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